Hyderabad Sep 27 2003 : Microarray technology, with its ability to provide global views of genome sequence and gene activity, results in vast amounts of gene expression data to be analyzed and managed. Genowiz™ aims to cater this need of the scientists and researchers actively using microarrays in their experiments, which by all estimates is growing exponentially.

Genowiz™ is a powerful program designed to analyze and visualize large scale datasets generated by high through put gene expression experiments using its comprehensive suit of advanced analysis methods. With a MIAME compliant backend relational database to ensures seamless, secure and effective data management and sharing across the lab members Genowiz™ stands as a total solution to a labs microarray data analysis and management needs.

HJD’s Dr. Ashok Amin, Director of the Rheumatology Research Laboratory and Laboratory for Functional and Pharmacogenomics, said, “Data analysis (storage, integration, annotation, statistical analysis and clustering) is a challenging task in this uncharted area of translational genomics. Ocimum Biosolutions has the tools to tackle the complexity. Dr. Steven Abramson (Chairman, Department of Rheumatology at HJD and New York University (NYU) Medical Center) and I are committed to exploring the hope and metamorphosis that pharmacogenomics brings into molecular medicine.”

Anuradha Acharya, CEO of Ocimum Biosolutions commented, “Genowiz has addressed issues that scientists face while dealing with microarray data in a structured manner using MIAME standards and also gives the researchers an edge as it is seamlessly integrated with the pathway editor”. She further added that, “This will ensure that we can go a level ahead in our quest for better drugs, diagnostics and microarray research”

She further added “Another added advantage in using Ocimum’s tools is the perpetual licensing structure, which makes Genowiz™ a tool which gives high value for their money.”

Some of the key features are:

1. “Ezee import wizard” to upload all available data formats. One click upload for Genepix, Scanalyze, Affymetrix and processed file.

2. Advanced Normalizaton Techniques including Global, Loess, Multiple slide, Dye Swap and normalization exclusive for the affymetrix chips.

3. Data reduction based on variability of expression, average expression, missing values, replicates, t-test, ANOVA.

4. Understanding relation among genes using Partitional clustering, Hierarchical clustering, Self organizing maps and Principle component analysis.

5. Visualize results as expression matrix, data table, MA plots, scatter graph, pie chart, line and bar graphs.

6. Sort data by gene identifier, description, average expression, variability in expression, distance from the selected genes and biological parameters.

7. Search data by gene identifier, description and other biological parameters.

8. Curated bio-database related to gene information including that of protein and metabolic pathways.

9. Information management as per MIAME guidelines.

10. Strong database support for tracking every analysis done by the user. Available in standalone and client server models.

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About Ocimum Biosolutions

Ocimum Biosolutions is an ISO 9001:2000 certified life sciences contract R&D Company provides cost-effective customized contract research services and next generation bioinformatics tools & services in the area of genomics, proteomics, laboratory information management (LIMS) for Biotech and Pharmaceutical industry. Ocimum Biosolutions is a Delaware registered company with its operations at Indianapolis, Indiana. The Indian arm of Ocimum Biosolutions is located at Hyderabad.

Contact Information
Name: Anuradha Acharya
Company: Ocimum Biosolutions LLC.
Email: bdm@ocimumbio.com
Phone: (866)-227-7512 (Toll free in the US)

Vendor: Ocimum Biosolutions
Product Name: Genowiz 1.0

Availability:
Academic Single seat license: $ 950 USD
Commercial Single seat license: $ 1950 USD
Site/network license is also available
For more information: (866)-227-7512 or www.ocimumbio.com